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Inflammation Res
2021;11:e372
GHK-Cu is the most studied in research and skincare
The net effect in cell culture is increased deposition of structurally mature extracellular matrix
For instance, HSPA2 is upregulated in the testicular tissue of rats with varicocele (Panner Selvam and Agarwal, 2021)
IS is approximately 90% bound to albumin in blood circulation and is primarily secreted and excreted through organic anion transporters (OAT1 and OAT3) in renal proximal tubules (113)
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